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Papillon Lefevre Syndrome

Treatment No. : RD0519
Dosage & Instructions: 15 drops in 15 ml of plain water twice a day, mornings and evenings.
Composition:
Ferr met D15+100C
Calc phos D6+60C
Chamomilla D3+30C
Lecithinum D15+100C
Nat carb D6+60C
Pepsinum D6+60C
Ferr phos D6+60C
Treatment Type:
This remedy is a symptomatic treatment. A symptomatic treatment cannot eliminate the disease from its root but is able to considerably improve the patient's condition by easing his or her symptoms.
Contra-indications: None established
Special Instructions: Whereas this remedy can be safely used by teenagers, its use has not been evaluated in children under 12 years of age. Please do not administer to children under this age.
Storage: Store in a cool and dry place
Precautions: Keep away from the reach of children
Standard Packaging : 30 ml Drops

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One 30 ml bottle for $79.99
Two 30 ml bottles for $129.99

 

Condition Overview:

Papillon-Lefevre Syndrome (PLS) is an extremely rare genetic disorder that typically becomes apparent from approximately one to five years of age. PLS is characterized by the development of dry scaly patches on the skin of the palms and the soles (palmar-plantar hyperkeratosis) in association with severe inflammation and degeneration of the structures surrounding and supporting the teeth (periodontium). The primary (deciduous) teeth frequently become loose and fall out by about age five. Without treatment, most of the secondary (permanent) teeth may also be lost by approximately age 17. Additional symptoms and findings associated with PLS may include frequent pus-producing (pyogenic) skin infections, abnormalities of the nails (nail dystrophy), and excessive perspiration (hyperhidrosis).

Papillon-Lefevre Syndrome is transmitted as an autosomal recessive trait. Genetic analysis of several affected families (kindreds) suggests that the disorder may result from changes (mutations) of a gene that regulates production of an enzyme known as cathespin C. The gene is located on the long arm (q) of chromosome 11 (11q14).

 

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