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Duane Syndrome
Condition Overview: Duane syndrome (DS) is an eye movement disorder present at birth (congenital) characterized by a limited ability to move the eye inward toward the nose (adduction), outward toward the ear (abduction), or in both directions. In addition, when the affected eye(s) moves inward toward the nose, the eyeball retracts (pulls in) and the eye opening (palpebral fissure) narrows. In some cases, when the eye attempts to look inward, it moves upward (upshoot) or downward (downshoot).Duane syndrome falls under the larger heading of strabismus (misalignment of the eyes) under the subclassification of incomitant strabismus (misalignment of the eyes that varies with gaze directions) and subheading of extraocular fibrosis syndromes (conditions associated with fibrosis of the muscles that move the eyes). Although the "muscle fibrosis" association suggests that syndromes under this heading are primary disorders of muscle, evidence suggests that DS (and other syndromes under this heading) may be primary disorders of nerve "innervation" (the distribution or supply of nerves). Duane syndrome has been subdivided clinically into three types: Type 1, Type 2, and Type 3. |
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