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Crigler Najjar Syndrome Type I

Treatment No. : RD0160
Dosage & Instructions: 15 drops in 15 ml of plain water twice a day, mornings and evenings.
Composition:
Chelidonium D2+20C
Cardus Mar D3+30 C
Hydrastis D4+40C
Secale Coe D7+70C
Podophyllum D10+100C
Terebinthina D10+100C
Fel Tauri D7+70C
Leptandra D30+100C
Treatment Type:
This remedy is a symptomatic treatment. A symptomatic treatment cannot eliminate the disease from its root but is able to considerably improve the patient's condition by easing his or her symptoms.
Contra-indications: None established
Special Instructions: Whereas this remedy can be safely used by teenagers, its use has not been evaluated in children under 12 years of age. Please do not administer to children under this age.
Storage: Store in a cool and dry place
Precautions: Keep away from the reach of children
Standard Packaging : 30 ml Drops

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One 30 ml bottle for $79.99
Two 30 ml bottles for $129.99

 

Condition Overview:

Crigler-Najjar syndrome type I is a very rare inherited metabolic disorder characterized by the complete absence of the enzyme uridine diphosphate glucuronosyltransferase (UDPGT), which is normally found in the liver. This enzyme is required for the conversion (conjugation) and subsequent excretion of bilirubin from the body. When UDP-glucuronosyltransferase activity is absent, these metabolic processes are hampered and abnormally high levels of bilirubin accumulate in the blood (hyperbilirubinemia).

Within the first few days of life, most infants with Crigler-Najjar syndrome type I develop persistent yellowing of the skin, mucous membranes, and whites of the eyes (jaundice). In addition, some affected individuals may develop kernicterus, a potentially life-threatening neurological condition in which toxic levels of bilirubin accumulate in the brain, causing damage to the central nervous system. Early signs of kernicterus may include lack of energy (lethargy), vomiting, fever, and/or unsatisfactory feedings. More serious signs of kernicterus may develop, including abnormal muscle rigidity, resulting in muscle spasms (dystonia) and involuntary movements of the limbs and/or entire body (athetosis). Crigler-Najjar syndrome type I is inherited as an autosomal recessive genetic trait.
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