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Amelogenesis Imperfecta
Condition Overview: Amelogenesis Imperfecta is a rare inherited disorder characterized by brown discoloration of the teeth, resulting from a lack calcium (hypocalcification) or underdevelopment (hypoplasia) of the hard outer covering of teeth (enamel). The disorder is divided into numerous forms based on the severity of the enamel defect (e.g., complete absence [agenesis], underdevelopment, etc.). Individuals with Amelogenesis Imperfecta may be prone to early tooth loss and/or disease of the structures that surround and support the teeth (periodontal disease). Amelogenesis Imperfecta may be inherited as an X-linked, autosomal dominant, or autosomal recessive genetic trait, depending on the form present. |
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